Browsing by Author "Yetunde Grace Ogunsanya"
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Item Prevalence of dengue virus antigenemia in the malaria endemic area of the southwest Nigeria(2018-02-16) Olayiwola, John Olusola; Nassar Adebayo Sulaiman; Yetunde Grace OgunsanyaDengue virus infection is an important arthropod borne disease that is common in the tropics because of the occurrence of the vector. Therefore, this study was carried out to investigate the occurrence of antibody in the serum of subjects. Cross sectional study was embarked upon on 80 consented patients with febrile conditions with informed consent and subsequently obtaining ethical approval. Demographic data was study using structured questionnaire. Blood samples were collected from the consented subjects and assay for anti-dengue antibody using Enzyme Linked Immunosorbent Assay (ELISA). The statistical analysis was carried out at p-value ≤ 0.05. The sex distribution of the subjects showed 35 (45%) male and 44 (55%) female, and 29 (36%) of the subjects knew that malaria is not the only cause of fever. Recent febrile illness was observed among 35 (44%) of the studied population while all subjects have had previous episodes of malaria. The distribution of antibody showed that 20 (55.6%) had dengue IgG antibody while 2 (5.6%) had dengue IgM antibody among the male and 22 (50%) had dengue IgG antibody while only 2 (4.5%) had dengue IgM antibody among female. The occurrence of dengue antibody among the subjects with recent febrile illness revealed that 3 (8.6%) had IgM antibody, while 13 (37.1%) had IgG antibody in their serum. The occurrence of anti-dengue antibody in this study further confirmed that there is re-emergence of dengue in tropical countries, such as Nigeria.