Ebola Virus Disease and Its Antecedents in West African Countries: Challenges, the Current Trend and the Way Forward
| dc.contributor.author | Olayiwola, John Olusola | |
| dc.contributor.author | Bakarey A. S. | |
| dc.date.accessioned | 2026-06-28T17:06:12Z | |
| dc.date.available | 2026-06-28T17:06:12Z | |
| dc.date.issued | 2017-10-27 | |
| dc.description.abstract | In 2017, Democratic Republic of Congo, a West African country experienced another outbreak of Ebola Virus Disease (EVD) since the largest outbreaks in history were last reported in 2015 in the region. Ebola virus disease is a severe, often fatal illness, with a death rate as high as 90% and caused by Ebola virus. The victims become infected with the pathogen either through contact with infected animals or via direct contact with the bodily fluids of infected humans. The virus responsible for this outbreak, the Zaire Ebola Virus (EBOV), from the genus Ebolavirus in conjunction with the genus Marburgvirus forms the Filoviridae family. Ebola virus is one of the most deadly and highly virulent pathogens among the viral haemorrhagic fevers resulting in case fatality rates of close to 90% as earlier documented. Multi-organ failure and severe bleeding complications have been responsible for the high mortality usually reported. In the recent past, a total of 5335 cases (confirmed, suspected and probable) with 2622 deaths, with a case fatality rate of around 50% have been documented. Laboratory confirmation through the use of RT-PCR molecular technique remains the gold standard for diagnosis. Although as at today, there is no licensed vaccine against the virus, however, under an agreement between GAVI and Merck, the developer of an Ebola vaccine known as rVSV-ZEBOV is now available. Therefore, various hygienic and preventive measures have been advocated for Ebola control and prevention. This review summarizes the drifts and pattern of Ebola outbreaks and its antecedents in West African region including other aspects of diagnosis and prevention and what is the current trend as a guide against future control | |
| dc.identifier.uri | https://repository.acu.edu.ng/handle/123456789/1912 | |
| dc.subject | Ebola virus disease | |
| dc.subject | Outbreaks | |
| dc.subject | Antecedents | |
| dc.subject | West Africa | |
| dc.subject | Prevention and control | |
| dc.title | Ebola Virus Disease and Its Antecedents in West African Countries: Challenges, the Current Trend and the Way Forward |
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